Patent · US Expired

Quantitative determination of the surface charge of serum lipoproteins

US4328000A · kind A · utility

8Cited by

5References

6Claims

0Family size

Assignee

BASF SE

Inventors

Dieter Horn · Heidelberg, DE
Erik Lueddecke · Mutterstadt, DE
Claus-Christian Heuck · Wilhelmsfeld, DE

Key dates

Filing date	Aug 15, 1980
Grant date	May 4, 1982
Priority date	—
Expiry date	Aug 15, 2000

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/044
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Disclosed is the polyelectrolytic titration of serum lipoproteins, the negative surface charge of the latter being determined quantitatively by adding an excess amount of a polycation in aqueous solution to the particular serum lipoprotein and then back-titrating the positive charge, of the polycation, which has not been neutralized by the negative surface charge, against a chromotropic polyanion, in the presence of a metachromatic dye as the indicator. The method according is used for the diagnosis of lipometabolic disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.