Ionic 5-C-substituted 2,4,6-triiodoisophthalic acid derivatives

US4328202A · kind A · utility

Assignee

• Schering A.G. · DE

Inventors

• Heinz Gries · Berlin, DE
• Heinrich Pfeiffer · Eppingen, DE
• Ulrich Speck · Berlin, DE
• Wolfgang Muetzel · Berlin, DE

Key dates

• Filing date: Jan 9, 1981
• Grant date: May 4, 1982
• Expiry date: Jan 9, 2001

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S430/168
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Ionic compounds of the formula ##STR1## wherein X is --CONR.sub.1 R.sub.2, --CH.sub.2 NH.multidot.Acyl or --CH.sub.2 OH; Y is --NR.sub.3 R.sub.4, --NH.multidot.Acyl or OR.sub.5 ; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 can be identical or different, and each is hydrogen, C.sub.1-6 - alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, R.sub.5 is C.sub.1-6 alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, and Acyl, which can be the same or different in X and Y, is C.sub.2-6 -alkanoyl or C.sub.2-6 -alkanoyl substituted by 1-4 OH groups and/or by one C.sub.1-3 -alkoxy group, or a physiologically compatible salt thereof with an inorganic or organic base, have valuable properties as X-ray contrast agents.