Substituted steroid-spiro-oxazolidinone derivatives and a process for the preparation thereof
US4328221A · kind A · utility
2Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 24, 1980 |
| Grant date | May 4, 1982 |
| Priority date | — |
| Expiry date | Dec 24, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula (I) having aldosterone-antagonizing activity are disclosed ##STR1## wherein R.sub.3 and R.sub.4 are each C.sub.1 to C.sub.3 alkyl; and PA1 Z is one of the following groups ##STR2## wherein R.sub.1 is hydrogen or methyl; PA1 R.sub.6 is hydrogen, C.sub.1 to C.sub.3 alkylthio or C.sub.2 to C.sub.4 acylthio; and PA1 X is oxo, hydroximino, C.sub.1 to C.sub.3 alkoxyimino, carboxy-alkoxyimino wherein the alkoxy has 2 to 4 carbon atoms or a salt-converted carboxy-alkoxy-imino wherein the alkoxy has 2 to 4 carbon atoms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.