N-Substituted-quinolin-4-one-2-carboxic acid derivatives
US4328230A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1979 |
| Grant date | May 4, 1982 |
| Priority date | — |
| Expiry date | Mar 5, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D221/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are described compounds of formula I, ##STR1## in which R.sub.5 to R.sub.8 may be a variety of substituents, or an adjacent pair of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a chain EQU --COCH.dbd.C(COOH)NRh--, or one of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a group of formula II, ##STR2## in which Ra, Rb and Rc have the same significances as R.sub.5, R.sub.6, R.sub.7 and R.sub.8, PA1 X is an optionally interrupted or substituted hydrocarbon chain, PA1 Rg and Rh, which may be the same or different are each alkyl, alkenyl, phenyl-alkyl, alkanoyl, benzoyl or phenylalkanoyl, PA1 or Rg and R.sub.8 and/or Rh and Rc in formula II, together form a chain --(CH.sub.2).sub.n --, and n is 2, 3 or 4. There are also described processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.