Mesoionic antitumor compositions and methods for using the same in the treatment of cancer

US4329355A · kind A · utility

Inventors

• David W. Henry · Chapel Hill, US
• Kenneth Ryan · New York, US
• Edward W. Grange · Palo Alto, US

Key dates

• Filing date: Mar 1, 1979
• Grant date: May 11, 1982
• Expiry date: Mar 1, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D273/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Mesoionic anhydro-5-amino-1,2,3,4-oxatriazolium hydroxides and methods of using the same in the treatment of cancer, said compositions containing, as an active ingredient, one or more compounds having the structure ##STR1## wherein R.sup.1 represents a phenyl or substituted phenyl group and R.sup.2 represents hydrogen or a methyl group.