3-Aryl-3-aryloxypropylamines
US4330546A · kind A · utility
1Cited by
5References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 3, 1980 |
| Grant date | May 18, 1982 |
| Priority date | — |
| Expiry date | Sep 3, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3-Aryl-3-aryloxyalkylamines of the general formula (I) ##STR1## and their pharmaceutically acceptable acid addition salts, wherein R.sup.1, R.sup.2, R.sup.4 and R.sup.5 are hydrogen or lower alkyl, R.sup.3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl, lower alkoxy, nitro or amino groups, and Ar.sup.1 is methylsulphinyl, methylsulphonyl- or cyano-substituted phenyl, 2- or 4-pyridyl, 2-pyrazinyl, 2-quinolinyl, 2-thienyl or 2-thiazolyl exhibit activity on the central nervous system, e.g. as antidepressants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.