Oxoimidazolinealkanoic acids and their salts and esters, their preparation and pharmaceutical compositions containing them

US4330550A · kind A · utility

Assignee

• A NATTERMANN & CIE GMBH · DE

Inventors

• Hans-Heiner Lautenschlager · Pulheim, DE
• Hans Betzing · Kerpen, DE
• Brigitte Stoll · Pulheim, DE

Key dates

• Filing date: Aug 15, 1980
• Grant date: May 18, 1982
• Expiry date: Aug 15, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D263/38
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

.omega.-(2-Oxo-4-imidazolin-1-yl) alkanoic acids and salts and esters thereof of the formula: ##STR1## in which n denotes an integer from 1 to 8, R.sup.1 denotes H, a non-toxic cation or a straight-chain or branched, saturated hydrocarbon group of 1 to 6 carbon atoms, and R.sup.2 denotes an unsubstituted or substituted aromatic radical of formula ##STR2## or naphthyl, the substituents X and Y being identical or different and each representing H, halogen or alkoxy have strong antithrombotic activity and an analgesic effect.