Diagnostic agent for the detection of leukocytes and chromogens useful therein

US4331760A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Dieter Berger · Viernheim, DE
• Franz-Josef Braun · Rimbach, DE
• Gunter Frey · Ellerstadt, DE
• Werner Guthlein · Mannheim, DE
• Wolfgang Werner · Hersbruck, DE

Key dates

• Filing date: May 25, 1979
• Grant date: May 25, 1982
• Expiry date: May 25, 1999

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Diagnostic agent for the detection of leukocytes in body fluids, comprising an absorbent carrier which is impregnated with a chromogen and a buffer substance, wherein the chromogen is a sulfonphthalein ester of the formula ##STR1## wherein R.sub.1 is a carboxylic acid residue optionally substituted by halogen or lower alkoxy; or is an amino acid or peptide residue having a nitrogen protective group; PA1 R.sub.2 is a halogen atom or a lower alkyl radical; and PA1 R.sub.3 and R.sub.4 are individually selected from hydrogen and halogen. Certain of the chromogen are provided as novel compounds.