Process for the monohalogenation of alkylbenzenes in the .alpha.-position and new alkylbenzenes monohalogenated in the .alpha.-position

US4331821A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rudiger Schubart · Wittlich, DE
• Erich Klauke
• Klaus Naumann
• Rainer Fuchs · Halver, DE

Key dates

• Filing date: Nov 24, 1980
• Grant date: May 25, 1982
• Expiry date: Nov 24, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C323/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the monohalogenation of alkylbenzenes in the .alpha.-position is disclosed wherein an alkylbenzene reactant containing a hydrogen atom in the .alpha.-position is contacted with a halogen and the reaction mixture is withdrawn such that the amount of monohalogenated alkylbenzene formed is no greater than 33 mol percent in the reaction mixture. Also disclosed are novel monohalogenated alkylbenzenes of the formula ##STR1## in which R.sup.7 represents trifluoromethoxy, trifluoromethylthio or 2-perfluoropropyl or also, if R.sup.8 represents chlorine, represents trifluoromethyl and, furthermore, if PA1 R.sup.8 and R.sup.9 represent trifluoromethyl, represents hydrogen, PA1 R.sup.8 represents hydrogen or also, if R.sup.7 represents trifluoromethyl or trifluoromethoxy, represent chlorine and also, if R.sup.7 represents hydrogen and R.sup.9 represents trifluoromethyl, denotes trifluoromethyl and PA1 R.sup.9 represents hydrogen and, if R.sup.7 represents hydrogen and R.sup.8 represents trifluoromethyl, denotes trifluoromethyl.