16 .alpha.-Alkyl steroids, their preparation, and pharmaceutical preparations thereof

US4333928A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Gunter Neef · Berlin, DE
• Ulrich Eder · Berlin, DE
• Gregor Haffer · Berlin, DE
• Gerhard Sauer · Berlin, DE
• Rudolf Wiechert · Berlin, DE
• Hermann Steinbeck · Berlin, DE

Key dates

• Filing date: May 16, 1980
• Grant date: Jun 8, 1982
• Expiry date: May 16, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J41/0088
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

16 .alpha.-Alkyl steroids of the formula ##STR1## wherein R.sub.1 is hydrogen or methyl, PA1 R.sub.2 is hydrogen, alkyl, acyl, or glycosyl PA1 R.sub.3 is hydrogen or a substituted or unsubstituted, saturated or unsaturated lower hydrocarbon residue, and PA1 R.sub.4 is methyl, ethyl or propyl, exhibit strong progestational activity and a very low androgenic activity.