Adsorbent for the affinity-specific separation of macromolecular materials

US4335226A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Werner Muller · East Greenwich, US
• Hans Bunemann · Steinhagen, DE

Key dates

• Filing date: Feb 24, 1978
• Grant date: Jun 15, 1982
• Expiry date: Feb 24, 1998

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/1006
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Adsorbents are provided for the affinity-specific separation of macromolecular materials, particularly biopolymers, the adsorbents comprising a polymeric carrier on to which an affine residue for the macromolecular material is covalently bound, either directly or via polymeric spacer. Preferred affine residue is comprised of a specific complex formers which are base-specific and/or structure specific for the macromolecular material. The invention also provides novel complex formers comprising a certain dyestuff residues and processes for their preparation.