Process for preparing vitamin D-lactones
US4336193A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 26, 1981 |
| Grant date | Jun 22, 1982 |
| Priority date | — |
| Expiry date | Jan 26, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J17/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides methods for preparing the various isomeric forms of 25-hydroxyvitamin D.sub.3 -26,23-lactone utilizing cyanohydrin formation with readily prepared steroid materials followed by actinic radiation of the products and recovery of the desired 25-hydroxyvitamin D.sub.3 -26,23-lactone. The invention also provides new intermediate compounds in their various isomeric forms derived during the process for preparing the said vitamin D.sub.3 lactones. 25-Hydroxyvitamin D.sub.3 -26,23-lactone is recognized as having vitamin D-like activity and is believed to play an important role in the regulation of calcium and phosphate levels in the animal and human organism. The present invention provides a convenient method for preparing the various isomeric forms of this compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.