1,4-Cycloalkano-oxazepines, salts thereof and analgesic uses thereof

US4336263A · kind A · utility

Assignee

• BASF SE

Inventors

• Hans-Jörg Treiber · Münstermaifeld, DE
• Dieter Lenke · Ludwigshafen, DE
• Wolfgang Worstmann · Havelsee, DE

Key dates

• Filing date: Jun 26, 1980
• Grant date: Jun 22, 1982
• Expiry date: Jun 26, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D267/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to novel 1,4-cycloalkano-oxazepines of the general formula ##STR1## where R.sup.1 is hydrogen, hydroxyl or alkoxy or acyloxy of 1 to 4 carbon atoms, R.sup.2 is a hydrocarbon radical of 1 to 3 carbon atoms, n is 1, 2 or 3 and x is 0 or 1, and of its salts with physiologically acceptable acids; processes for their preparation, and their use in therapy. The novel substances are suitable for the pharmacotherapy of pains of various origins.