Process for preparing high purity ursodeoxycholic acid
US4337206A · kind A · utility
3Cited by
2References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 29, 1981 |
| Grant date | Jun 29, 1982 |
| Priority date | — |
| Expiry date | Apr 29, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J51/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing 3.alpha., 7.beta.-dihydroxy-cholanic acid (I) from 3.alpha., 7.alpha.-dihydroxy-.DELTA..sub.11 -cholenic acid. This starting substance is converted by oxidation and successive reduction into 3.alpha., 7.beta.-dihydroxy-.DELTA..sub.11 -cholenic acid, which is separated in the form of the tris-trimethylsilyl derivative of high purity. The product (I) is obtained by hydrogenating and hydrolyzing the trisilyl derivative.
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