Phenalkoxyalkyl- and phenoxyalkyl-substituted oxiranecarboxylic acids, their use and medicaments containing them

US4337267A · kind A · utility

Assignee

• Byk Gulden Lomberg Chemische Fabrik GmbH · DE

Inventors

• Klaus Eistetter · Konstanz, DE
• Erich Rapp · Radolfzell, DE

Key dates

• Filing date: Apr 3, 1981
• Grant date: Jun 29, 1982
• Expiry date: Apr 3, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C43/29
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Phenalkoxyalky- and phenoxyalkyl-substituted oxiranecarboxylic acids of the formula ##STR1## wherein R.sup.1 denotes a hydrogen atom (--H), a halogen atom, a lower alkyl group, a lower alkoxy group, a nitro group or a trifluoromethyl group, PA1 R.sup.2 has one of the meanings of R.sup.1, PA1 R.sup.3 denotes a hydrogen atom (--H) or a lower alkyl group, PA1 Y denotes --O--(CH.sub.2).sub.m --, PA1 m denotes O or an integer from 1 to 4, and PA1 n denotes an integer from 2 to 8, with the proviso that the sum of m and n is an integer from 2 to 8, and the salts of the acids are new compounds. They display a hypoglycaemic action in warm-blooded animals. Processes for the preparation of the new compounds and of the intermediate products required for their preparation are described.