Method of using over the counter swab kit for self detection of gonorrhea in the male using tetramethyl chromogen ampul
US4340670A · kind A · utility
Inventor
Key dates
| Filing date | Jun 19, 1981 |
| Grant date | Jul 20, 1982 |
| Priority date | — |
| Expiry date | Jun 19, 2001 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/871
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An over the counter swab kit for self detection of gonorrhea in the male using an ampul containing 1% N, N, N' N' tetramethyl-p- phenylenediamene or tetramethyl chromogen. The method of taking a sample is also shown in which the open end of a tube is filled with a plug in the form of fibrous material. After a sample is taken of exudate from a male, the 1% solution of tetramethyl chromogen reacts with Neisseria gonorrhea which may be present in the exudate to produce a color change. The plug, before the test, is in a dry condition, the plug is activated only by the tetramethyl chromogen which is placed below the plug in the tube and the ampul broken to release its contents. A sufficient amount of 1% tetramethyl chromogen is held within the frangible ampul to wet the plug and this amount is 1/2 the volume than is used in the saline ampul in my companion patent application entitled Over the Counter Swab Kit for Self Detection of Gonorrhea in the Male Using Saline Ampul. This volume is drawn by capillary action through the tip on which the sample of exudate was placed and before the ampul was broken. A purple color is created on the tip in 3 minutes at the site of the bacteria and is a…
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