Optical sensor of plasma constituents
US4344438A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 28, 1980 |
| Grant date | Aug 17, 1982 |
| Priority date | — |
| Expiry date | Apr 28, 2000 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/7786
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for monitoring low molecular weight compounds in blood plasma in the body by optical means includes a chamber which can be inserted into the blood stream and which contains specific receptor sites for the plasma constituent to be analyzed. The chamber interior is isolated from the blood by a dialysis membrane which permits the plasma constituents to diffuse into the chamber. A competing ligand for the receptor sites is placed within the chamber, but due to its relatively large molecular size the competing ligand cannot escape through the dialysis membrane into the bloodstream. Light emitted or absorbed by the competing ligand gives a measure of the concentration of the selected low molecular weight compounds in the blood.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.