Preparation of 2-hydroxyalkylchromans

US4344886A · kind A · utility

Assignee

• BASF SE

Inventors

• Michael Horner · Neustadt, DE
• Axel Nissen

Key dates

• Filing date: Feb 26, 1981
• Grant date: Aug 17, 1982
• Expiry date: Feb 26, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D311/58
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

2-Hydroxyalkylchromans (I) ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each H or C.sub.1 -C.sub.8 -alkyl, R' is H or an organic radical which can be split off hydrolytically or hydrogenolytically as R'-OH or R'-COOH, and m is 1, 2 or 3, are prepared by reacting a hydroquinone II ##STR2## (a) with an alkenediol IIIa ##STR3## or (b) with an alkenediol IIIb ##STR4## or (c) with an alkenediol IIIc ##STR5## where R.sup.4' is a radical which during the condensation with II is converted to the radical R.sup.4, at from -50.degree. C. to 120.degree. C., in an inert solvent, in the presence of from 10 to 300 mole %, based on II, of a Lewis acid or of an adduct of a Lewis acid with a Lewis base which has a lower basicity than compound II.