Patent · US Expired

Antiandrogenic 17.alpha.-substituted steroids

US4344941A · kind A · utility

35Cited by

2References

11Claims

0Family size

Assignee

Schering A.G. · DE

Inventors

Rudolf Wiechert · Berlin, DE
Dieter Bittler · Berlin, DE
Annerose Schleusener · Berlin, DE
Manfred Albring · Berlin, DE

Key dates

Filing date	Oct 20, 1980
Grant date	Aug 17, 1982
Priority date	—
Expiry date	Oct 20, 2000

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

17.alpha.-substituted steroids of the formula ##STR1## wherein R.sub.1 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, PA1 R.sub.2 is alkyl or alkenyl of 2-6 carbon atoms, PA1 X is oxygen or the grouping H(OR.sub.3) wherein R.sub.3 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, upon topical application, display antiandrogenic properties and can be utilized for the treatment of acne, seborrhea, alopecia and hirsutism.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.