Method of producing N-benzyloxycarbonyl-L-aspartic acid
US4345091A · kind A · utility
6Cited by
2References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 12, 1981 |
| Grant date | Aug 17, 1982 |
| Priority date | — |
| Expiry date | Jan 12, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0613
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The reaction between L-aspartic acid and benzyloxycarbonyl chloride is carried out at a specific pH range, i.e., 12.0 to 13.5, whereby highly pure N-benzyloxycarbonyl-L-aspartic acid can be obtained in high yields, while both the by-production of N-benzyloxycarbonyl-.alpha.- or .beta.-L-aspartyl-L-aspartic acid and the decomposition of benzyloxycarbonyl chloride to benzyl alcohol are suppressed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.