Cyclization process to form cephem ring
US4346218A · kind A · utility
13Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 1980 |
| Grant date | Aug 24, 1982 |
| Priority date | — |
| Expiry date | Feb 27, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An intermediate represented by following formula for synthesizing 3-hydroxy-3-cephem compounds ##STR1## wherein A and B each is a hydrogen or amino substituent; R is a hydrogen or thiol substituent; Hal is a halogen; X is a hydroxy or carboxy protecting group; the broken line between A and R shows that when R and B are hydrogens, and A is a carboxylic acyl, the substituents can be combined to form an azetidinothiazoline bicyclic ring; and the enamine derivatives thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.