New derivatives of 2,4,6-triiodo-isophthalic acid, proceses for their synthesis and X-ray contrasting materials containing these
US4348377A · kind A · utility
35Cited by
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7Claims
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Key dates
| Filing date | Jul 30, 1980 |
| Grant date | Sep 7, 1982 |
| Priority date | — |
| Expiry date | Jul 30, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-(.alph a.-hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.