Use of polypeptides as analgesic drugs

US4351829A · kind A · utility

Assignee

• Farmitalia Carlo Erba S.p.A. · IT

Inventors

• Gerhard Zetler · Lübeck, DE
• Alessandro Rossi · Milano, IT
• Chiara De Paolis · Milano, IT

Key dates

• Filing date: Sep 26, 1980
• Grant date: Sep 28, 1982
• Expiry date: Sep 26, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/595
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of treating pain of whatever origin and nature in human and animal which comprises administering to the patient in need an effective amount of a polypeptide of structure: ##STR1## wherein X is selected from the group consisting of hydrogen, t-butyloxycarbonyl(Boc), Asp, Pyr--Glu, Pyr--Gln--Asp, Pyr--Asn--Asp; PA1 Y is selected from the group consisting of Thr, Met, Leu, Nle, Val; PA1 W is selected from the group consisting of Met, Nle, Leu.