Novel 1-[3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl]-3-phenyl-1-propanones and their salts and a process for the preparation thereof
US4352819A · kind A · utility
3Cited by
1References
8Claims
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Assignee
Inventor
Key dates
| Filing date | Nov 25, 1981 |
| Grant date | Oct 5, 1982 |
| Priority date | — |
| Expiry date | Nov 25, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The disclosure is directed to novel 1-[3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl]-3-phenyl-1-propanones and their salts. The compounds of the invention have the structural formula ##STR1## in which R and R.sub.1 are independently hydrogen or methyl and R.sub.2 is n-propyl, n-butyl, isobutyl or tert-butyl. The compounds have an outstanding antiarrhytmical activity already in low doses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.