Patent · US Expired

Carrier having acrylate copolymer coating for immobilization of bioactive materials

US4352884A · kind A · utility

116Cited by
5References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 9, 1981
Grant dateOct 5, 1982
Priority date
Expiry dateFeb 9, 2001

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/962
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Carriers coated with a copolymer of a hydrophilic acrylate or methacrylate monomer and a copolymerizable unsaturated carboxylic acid or unsaturated amine are provided which are substantially free from nonspecific adsorption of proteins and the like. Due to the side-chain carboxyl or amino groups of the copolymer, these coated carriers are able to immobilize bio-active materials such as antigens, antibodies, complements and enzymes. These carriers, on which bio-active materials can be immobilized, are useful as clinical selective adsorbents, affinity-chromatographic adsorbents, selective electrodes or columns for analysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.