Peptides, process for preparation thereof and use thereof
US4354966A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1980 |
| Grant date | Oct 19, 1982 |
| Priority date | — |
| Expiry date | Oct 3, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/465
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to novel peptides and their pharmaceutically acceptable salts, particularly useful for pharmaceutical purposes such as in the therapeutic treatment of infectious diseases caused by pathogenic microorganisms. The compounds have the structure ##STR1## wherein R.sup.1 is hydrogen or acyl; PA1 R.sup.2 is carboxy or protected carboxy or a group of the formula: --COHN--R.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl; PA1 R.sup.3 is carboxy, protected carboxy, lower alkyl, hydroxyphenyl, carbamoyl or a group of the formula: ##STR2## wherein R.sub.a.sup.3 is hydrogen, amino, protected amino or acylamino, R.sub.b.sup.3 is carboxy or protected carboxy; PA1 R.sup.p is carboxy, protected carboxy, carbamoyl, carboxy (lower) alkyl or protected carboxy (lower) alkyl; PA1 l is an integer 2, PA1 m is an integer 0 to 2 and PA1 n is an integer 1, PA1 provided that, PA1 when PA1 R.sup.1 is hydrogen or acyl, PA1 R.sup.2 is carboxy, protected carboxy or a group of the formula: --CONHR.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl, PA1 R.sup.p is carboxy, or protected carboxy, m is an int…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.