Patent · US Expired

Synthesis of steroids

US4354972A · kind A · utility

3Cited by
2References
24Claims
0Family size

Inventor

Key dates

Filing dateAug 10, 1981
Grant dateOct 19, 1982
Priority date
Expiry dateAug 10, 2001

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J51/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to the synthesis of steroids which are useful for their biological activity or which may be converted to steroids which have such activity. These syntheses include the steroid compounds and processes for their preparation. An object of the invention is to provide syntheses which are applicable to materials which are readily available in good supply for converting such materials to steroids which are useful and desirable in the manufacture of pharmaceutical products. More particularly, I have sought to discover processes and intermediate compounds useful in the synthesis of 24, 25-dihydroxycholesterol from hyodeoxycholic acid or lithocholic acid which are constituents of, and readily available from, animal bile.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.