Time-release chemical delivery system
US4356166A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1978 |
| Grant date | Oct 26, 1982 |
| Priority date | — |
| Expiry date | Dec 8, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/645
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A time-release chemical delivery system in which a bioactive compound is attached to a polymeric biodegradable carrier by a hydrolyzable bond is disclosed. The bioactive compound can either be bound directly to the polymer or be attached to the polymer via a spacer group. The composition of the system is particularly effective for delivering medication systemically to a host animal over a prolonged period of time after being surgically implanted or injected subcutaneously. Biodegradable condensation polymers having reactive pendant groups, for example, poly-L-(glutamic acid), or derivatized poly-L-(glutamic acid) are effective as polymeric carriers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.