Phenoxyalkanolamine derivatives

US4356322A · kind A · utility

Assignee

• VEB Arzneimittelwrk Dresden · DE

Inventors

• Dieter Lehmann · Stuttgart, DE
• Klaus Femmer · Radebeul, DE
• Gottfried Faust · Berlin, DE

Key dates

• Filing date: Mar 24, 1980
• Grant date: Oct 26, 1982
• Expiry date: Mar 24, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C217/80
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A series of novel derivatives of phenoxyalkanolamine of the general formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and are hydrogen, alkyl of 1 to 2 carbon atoms, methoxy, halogen, nitro, amino or acylamino residues, and the salts thereof, are described, as are methods for their synthesis. The compounds are highly active .beta..sub.1 -specific sympathicomimetics with a partially antagonistic component.