Bis-hydroxymethyl carbonate bridged antibacterial agents
US4359472A · kind A · utility
3Cited by
7References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 22, 1981 |
| Grant date | Nov 16, 1982 |
| Priority date | — |
| Expiry date | Dec 22, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D499/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antibacterial agents in which a penicillin and a beta-lactamase inhibitor are linked by means of a bis-hydroxymethyl carbonate bridge are of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sup.1 is hydrogen, hydroxy, certain acyloxy or certain alkoxycarbonyloxy groups, a method for their use, pharmaceutical compositions thereof, and intermediates useful in their production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.