Process for the preparation of acyl cyanide compounds

US4360479A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Kurt Findeisen · Odenthal, DE
• Hans Kratzer · Wuppertal, DE
• Manfred Lenthe · Odenthal, DE

Key dates

• Filing date: Jun 24, 1981
• Grant date: Nov 23, 1982
• Expiry date: Jun 24, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C255/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to a new process for the preparation of acyl cyanides of the general formula EQU R.sup.1 --CO--CN (I) wherein R.sup.1 is an optionally substituted alkyl radical up to 18 carbon atoms, an optionally substituted cycloalkyl radical with 3 to 12 carbon atoms, an optionally substituted aryl radical or an optionally substituted 5- or 6-membered heterocyclic radical, which can additionally also be fused with a benzene ring, which process comprises reacting a carboxylic acid anhydride of the formula EQU R.sup.1 --CO--O--CO--R.sup.1 (II) with an alpha-hydroxynitrile of the formula ##STR1## in which R.sup.2 and R.sup.3 are identical or different and represent a hydrogen atom, an optionally substituted alkyl radical with 1 to 18 carbon atoms, an optionally substituted cycloalkyl radical with 3 to 12 carbon atoms, an optionally substituted aryl radical or an optionally substituted 5- or 6-membered heterocyclic radical, which can additionally also be fused with a benzene ring. The acyl cyanides (I) are known compounds and can be used as starting material for the synthesis of herbicides.