Process for treating and/or removal of substances from liquid, especially whole blood
US4361484A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 11, 1981 |
| Grant date | Nov 30, 1982 |
| Priority date | — |
| Expiry date | Feb 11, 2001 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J20/3242
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A process for the treating of and/or removal of substances from a liquid, especially whole blood, via a semipermeable microporous membrane (13, 14, 15) through adsorption and/or biological reaction by means of a biologically active material. Said whole blood is exposed to pressure variations at the membrane surface in a way such that a penetrating fraction of said whole blood is flowing in an alternating flow path through the membrane walls for contacting said biologically active material. Said biologically active material is asymmetrically immobilized in and on the surface of the side of said membrane that faces away from said whole blood. Alternatively, said biologically active material may be bound to an unsoluble matrix behind said membrane. Said membrane is for example provided within a casing (7, 8, 9) comprising inlet (10) and outlet (11) for said whole blood. The space between said casing and said membrane is via a connecting nipple (12) in communication with for example an expansion chamber for the provision of pressure variations. By means of the device (3) it is possible to perform said process in one and the same step and by means of one and the same pumping system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.