Fermentation process of preparing demethyl maytansinoids
US4361650A · kind A · utility
294Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 7, 1981 |
| Grant date | Nov 30, 1982 |
| Priority date | — |
| Expiry date | Aug 7, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/585
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel demethylmaytansinoids representable by the formula: ##STR1## (wherein X is Cl or H; R.sub.1 is H or acyl group) are produced from maytansinoids by means of enzymic transformation. The demethylmaytansinoids are useful as antifungal, antiprotozoal or antitumor agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.