Tissue adhesive

US4362567A · kind A · utility

Assignee

• Immuno Aktiengesellschaft fur chemisch-medizinische Produkte · AT

Inventors

• Otto Schwarz · Waldshut-Tiengen, DE
• Yendra Linnau · Wien, AT
• Franz Loblich · Wien, AT
• Thomas Seelich · Wien, AT

Key dates

• Filing date: Feb 4, 1980
• Grant date: Dec 7, 1982
• Expiry date: Feb 4, 2000

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/83
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A tissue adhesive on the basis of human or animal protein contains factor XIII and at least 33% by weight of fibrinogen, has a ratio of factor XIII to fibrinogen, expressed in units of factor XIII per gram of fibrinogen, of at least 80, contains fibrinogen and albumin in the total protein at a ratio of 33 to 90:5 to 40, contains plasminogen-activator-inhibitor or plasmin inhibitor in an amount of 250 to 25,000 KIU per g of fibrinogen and has been lyophilized.