Maytansinoids
US4364866A · kind A · utility
291Cited by
0References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 17, 1980 |
| Grant date | Dec 21, 1982 |
| Priority date | — |
| Expiry date | Sep 17, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/872
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Antibiotic C-15003 PHO of the formula: ##STR1## wherein R.sub.1 is H, hydroxyl, alkanoyloxy, alkenylcarbonyloxy or arylcarbonyloxy; R.sub.2 is H, hydroxyl or alkanoyloxy; R.sub.3 is H or alkanoyloxy is produced by introducing a hydroxyl group into 15-position of a maytansinoid compound, and, if desired, thus obtained compound is subjected to deacylation or acylation. Antibiotic C-15003 PHO is useful as antiprotozoal or antitumor agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.