Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof
US4367217A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 31, 1980 |
| Grant date | Jan 4, 1983 |
| Priority date | — |
| Expiry date | Dec 31, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.