Method for protecting guanidino group and restoring the same
US4368150A · kind A · utility
2Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 11, 1981 |
| Grant date | Jan 11, 1983 |
| Priority date | — |
| Expiry date | Feb 11, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/23
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A guanidino group in an amino acid or a peptide can be protected with a specific group, i.e. pentamethylbenzensulfonyl, 2,4,6-trimethoxybenzenesulfonyl, 4-methoxy-2,3,5,6-tetramethylbenzenesulfonyl, 4-methoxy-2,6-dimethylbenzenesulfonyl or 4-methoxy-2,3,6-trimethylbenzenesulfonyl, and said group may easily be removed without affecting the amino acid or the peptide to be derived from the protected amino acid or peptide. Thus, the present invention is useful in the synthesis of peptides containing the guanidino group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.