Patent · US Expired

Acylpeptides

US4369179A · kind A · utility

12Cited by
15References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1980
Grant dateJan 18, 1983
Priority date—
Expiry dateDec 5, 2000

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Acylpeptides derived from somatostatin or from a derivative thereof having analogous action, in which the amino acids sequence is modified by omitting individual amino acids and/or by exchanging them for other amino acids, and in which the .epsilon.-amino group of the lysine residue in the 9-position, and optionally also the .epsilon.-amino group of the lysine residue in the 4-position and/or the N-terminal .alpha.-amino group carries the acyl radical of an optionally substituted alkanecarboxylic acid, and salts and complexes thereof can be used as antidiabetics and/or for combating gastrointestinal bleeding. They are manufactured by conventional methods of peptide chemistry.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.