2-Pyridyl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors
US4369183A · kind A · utility
31Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1981 |
| Grant date | Jan 18, 1983 |
| Priority date | — |
| Expiry date | Feb 2, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D275/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns novel 2-aryl-1,2-benzisothiazolinone-1,1-dioxide compounds; methods for their preparation; pharmaceutical compositions containing them as an active ingredient; and methods of selectively inhibiting proteases, especially elastase, and of treating emphysema, rheumatoid arthritis, and various inflammatory diseases, for example, bronchial inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.