Recombinant deoxyribonucleic acid which codes for plasminogen activator

US4370417A · kind A · utility

Assignee

• Abbott Laboratories · US

Inventors

• Paul P. Hung · Via Enrico Fermi, US
• Shaw-Guang Lee · Libertyville, US
• Ranajit Roychoudhury · Wadsworth, US
• Barry J. Ratzkin · Houston, US
• W. Jurgen Schrenk · Weilheim, DE
• Michael C. Chen · Cambridge, GB

Key dates

• Filing date: Apr 3, 1980
• Grant date: Jan 25, 1983
• Expiry date: Apr 3, 2000

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/808
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides a deoxyribonucleic acid (DNA) segment related to a human plasminogen activator gene. The segment is inserted into a plasmid vector which in turn can be incorporated into a bacterium or other microorganism. The bacterium can then be cultured to produce a plasminogen activator protein having properties of human urokinase.