4,5-Deoxymaytansinoids, their use and pharmaceutical compositions thereof
US4371533A · kind A · utility
289Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 29, 1981 |
| Grant date | Feb 1, 1983 |
| Priority date | — |
| Expiry date | Sep 29, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to 4,5-deoxymaytansinoid compounds represented by the formula ##STR1## wherein X is a hydrogen atom or an alkyl or acyl group, Y is a hydrogen or chlorine atom, and R is a hydrogen atom or a carboxylic acid-derived acyl group, and methods of producing the same. The compounds are useful as antitumor, antiprotozoal and antifungal agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.