Compound having antitussive activity

US4372958A · kind A · utility

Assignee

• A. Menarini S.A.S. · IT

Inventors

• Vittorio Pestellini · Firenze, IT
• Mario Ghelardoni · Firenze, IT
• Danilo Giannotti · Altopascio, IT
• Alberto Meli · Firenze, IT
• Carlo Alberto Maggi · Firenze, IT

Key dates

• Filing date: Jun 10, 1981
• Grant date: Feb 8, 1983
• Expiry date: Jun 10, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D473/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A new compound 3(4-phenyl-1-piperazinio-1-yl)-1,2-propanediol 3(theophyllin-7-yl)-1-propanesulphonate, possesses antitussive action and is therefore usable in therapy. The compound is obtained by treating 3(theophyllin-7-yl)-1-propanesulphonic acid with 3(4-phenylpiperazin-1-yl)-1,2-propanediol in a suitable solvent.