Substituted 2-benzoyl-4-chloroglycinanilide derivatives, a process for their production, and their use as medicaments
US4372975A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 27, 1980 |
| Grant date | Feb 8, 1983 |
| Priority date | — |
| Expiry date | Oct 27, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to new substituted 2-benzoyl-4-chloroglycinanilide derivatives, to a process for their production and to their use as medicaments. The new derivatives according to the invention correspond to the general formula ##STR1## in which: R may be a linear or branched alkyl group, preferably a lower alkyl group; PA0 R.sub.1 and R.sub.2 may be the same or different and are selected from hydrogen, alkyl, alkenyl, alkynyl, hydroxy alkyl, alkoxy alkyl and aralkyl groups, these various groups optionally being linear or branched, and from 3- to 6-membered cycloalkyl groups optionally substituted on the .alpha.-carbon atom by an alkynyl radical; in addition, the groups R.sub.1 and R.sub.2 may form with the nitrogen atom to which they are attached an optionally saturated 5-membered or 6-membered nitrogen heterocycle optionally containing a second heteroatom selected from oxygen and nitrogen, said heterocycle optionally being substituted, preferably on the second nitrogen atom, by a lower alkyl radical; and their salts obtained with therapeutically acceptable mineral or organic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.