Novel compounds
US4374834A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 26, 1981 |
| Grant date | Feb 22, 1983 |
| Priority date | — |
| Expiry date | Mar 26, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/587
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel syn isomers of 7-[2-(2-amino-4-thiazolyl)-2-(carboxymethyloxyimino)-acetamido]-ceph-3-eme -4-carboxylic acid compounds of the formula ##STR1## wherein R is selected from the group consisting of alkyl of 1 to 3 carbon atoms and --CH.sub.2 --S--R.sub.1, R.sub.1 is an optionally substituted heterocyclic of 5 to 6 chain components with 1 to 4 heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen, A is selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, magnesium, --NH.sub.4, an easily cleavable ester and a non-toxic, pharmaceutically acceptable organic amine, A.sub.1 is selected from the group consisting of alkyl of 1 to 3 carbon atoms, hydrogen, alkali metal, alkaline earth metal, magnesium, --NH.sub.4, an easily cleavable ester and a non-toxic, pharmaceutically acceptable organic amine and non-toxic, pharmaceutically acceptable acid addition salts thereof having antibiotic activity and their preparation and intermediates therefor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.