5-ASA Drug delivery system
US4374932A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 8, 1981 |
| Grant date | Feb 22, 1983 |
| Priority date | — |
| Expiry date | Jun 8, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.