Intermediates for use in the preparation of cephalosporin antibiotics
US4374983A · kind A · utility
3Cited by
3References
1Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 3, 1981 |
| Grant date | Feb 22, 1983 |
| Priority date | — |
| Expiry date | Mar 3, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D501/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
(6R,7R)-7-amino-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylic acid monoperchlorate is a useful intermediate in the preparation of (6R,7R)-7-amino-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate dihydrochloride by enzymatic deacylation of 7-amino-3-(1-pyridiniummethyl) cephalosporin compounds and may be isolated in a substantially pure crystalline form. The said dihydrochloride and its solvates may be used as intermediates in the preparation of a wide range cephalosporin compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.