Cyclic diamine derivatives

US4374990A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Rolf-Ortwin Weber · Niedernhausen, DE
• Alfons Soder · Kelsterbach, DE
• Istvan Boksay · Kiedrich, DE

Key dates

• Filing date: Oct 26, 1979
• Grant date: Feb 22, 1983
• Expiry date: Oct 26, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound having the general formula or an acid addition salt thereof ##STR1## in which formula R.sub.1 is selected from the group consisting of PA1 (A) an at least mononuclear heterocyclic group having 4 to 10 carbon atoms in the ring system bound to the group ##STR2## through a carbon atom and containing at least one oxygen, nitrogen or sulphur atom, PA1 (B) substitution products of (A) containing at least one substituent selected from the group consisting of halogen, trifluoromethyl, hydroxy, alkoxy of 1 to 3 carbon atoms, unsubstituted amino, amino substituted by up to two alkyl groups each having 1 to 3 carbon atoms and alkyl groups having 1 to 6 carbon atoms, PA0 X is oxygen, sulphur or an NH-group, PA0 Y is an alkylene group having 1 to 3 carbon atoms in the chain, or an alkylene group having 1 to 3 carbon atoms in the chain substituted by (a) up to 3 alkyl groups each having up to 3 carbon atoms and a total of not more than 8 carbon atoms, or (b) substituted by one or two phenyl groups, PA0 R.sub.2 is selected from the group consisting of PA1 (c) an at least mononuclear carbocyclic or heterocyclic group having 4 to 10 carbon atoms in the ring system, containing but one het…