Biologically pure culture of Actinoplanes missouriensis
US4375513A · kind A · utility
10Cited by
5References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 9, 1981 |
| Grant date | Mar 1, 1983 |
| Priority date | — |
| Expiry date | Oct 9, 2001 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibiotic A-4696 factors B.sub.1, B.sub.2, B.sub.3, C.sub.1a, C.sub.3, and E.sub.1 are isolated from antibiotic A-4696, the latter being produced by Actinoplanes missouriensis strains ATCC 31680, ATCC 31682, and ATCC 31683 under submerged aerobic conditions in a culture medium and isolated from the fermentation broth by absorption on an ion exchange resin and eluted therefrom at p.sup.H 10.5 with sodium hydroxide. The novel factors are separated by thin layer chromatography and high pressure liquid chromatography and have antimicrobial and growth promotant activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.