Immunometric assays using monoclonal antibodies
US4376110A · kind A · utility
1,194Cited by
5References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 4, 1980 |
| Grant date | Mar 8, 1983 |
| Priority date | — |
| Expiry date | Aug 4, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/971
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
"Two-site" or "sandwich" immunometric assay techniques for determination of the presence and/or concentration of antigenic substances in fluids using monoclonal antibodies. One monoclonal antibody is presented in a soluble labeled form and a second monoclonal antibody is presented bound to a solid carrier; the soluble and bound monoclonal antibodies may be the products of either the same or different cell lines. Each monoclonal antibody has an affinity for the antigenic substances of at least about 10.sup.8 liters/mole.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.