Cyclic acetals of glutamic acid-.gamma.-semialdehyde, process for their production and use

US4376864A · kind A · utility

Assignee

• Degussa AG · DE

Inventors

• Karlheinz Drauz · Alzenau, DE
• Axel Kleemann · Hanau, DE
• Marc Samson · Lokeren, BE

Key dates

• Filing date: Nov 10, 1981
• Grant date: Mar 15, 1983
• Expiry date: Nov 10, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D319/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention is directed to cyclic acetals of glutamic acid-.gamma.-semialdehyde of the formula ##STR1## in which A is an unsubstituted alkylene group having 2 to 3 carbon atoms or such an alkylene group substituted by 1 to 2 methyl groups and to a method of producing a compound of formula (I) by reaction of a compound of the general formula ##STR2## in which A is as defined above with hydrogen cyanide or a cyanide ion supplying compound, ammonia or an ammonium ion supplying compound and carbon dioxide or a carbonate ion supplying compound and basic hydrolysis of the reaction mixture obtained and to using the compound of formula (I) to produce D,L-proline.